NASDAQ · TLPHHealthcarePharmaceuticals

Talphera, Inc. Common Stock (TLPH)

$1.05+0.96%
Close Nov 4, 2026 · split-adjusted
Nov 4, 2026$1.05▼ 17.97% in range
Nov 4, 2025Low $0.72 · High $1.47Nov 4, 2026
What changed · written from our data
As of Nov 4, 2026

Talphera closed at $1.05 on Nov 4, up 0.96%, 28.6% below its 52-week closing high. Volume of 92.5K shares was 1.35× its 20-day average (above normal).

Split-adjusted performance: -5.4% over one month, +20.7% over six months, -25.5% over one year.

Short interest was 1.1M shares at the Oct 15 settlement, up 47.7% from the prior report (4.1% of float, 6.2 days to cover).

Market cap$54.5M51.9M shares
Revenue · quarter$0.00—
Diluted EPS$-0.06—
P/E · TTM—P/S 54,501.1×
Net margin—
Dividend yieldNone
52-week range0.72 – 1.47−28.6% from high
Volume92.5K1.35× 20-day avg
Volatility · 60d42.5%Annualised
Short % of float4.1%6.3 days to cover
Net cash$17.1MCash $17.1M
Next earnings—Not scheduled
Split-adjusted performance
1W −3.7%1M −5.4%3M −26.6%6M +20.7%YTD −7.9%1Y −25.5%3Y —5Y —

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum82
Revenue growth—
Net margin—
Value (low P/E)—
Size32

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short1.1M+47.7% vs prior
Days to cover6.3Settled Oct 15
% of float4.1%
Short vol. 10d53.5%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
TLPHTalphera$1.05+0.96%+20.7%———$54.5M
OSTXOS Therapies Incorporated$1.15−0.86%−33.5%———$53.8MCompare
BOLDBoundless Bio$2.40+0.84%+51.9%———$55.5MCompare
ONCYOncolytics Biotech$0.4248+8.92%−53.8%———$55.7MCompare
RFLRafael Holdings$1.07−0.93%−14.4%−30.3%−3760.7%—$55.8MCompare
HOWLWerewolf Therapeutics$1.09+1.87%+67.6%—17.5%—$53.0MCompare
PLRXPliant Therapeutics$0.8518−1.03%−30.7%———$52.7MCompare
HRTXHeron Therapeutics$0.2986+4.88%−77.2%+1.3%−14.6%—$56.7MCompare
RNTXRein Therapeutics$0.6587−1.32%−43.7%———$56.8MCompare

Quick answers

What does Talphera do?
Talphera Inc. is a pharmaceutical company focused on the development and commercialization of therapies for use in medically supervised settings.
What is TLPH's market cap?
$54.50M, based on the Nov 4 close of $1.05.
Does Talphera pay a dividend?
No regular cash dividend has been paid in the last year.
How much of TLPH is sold short?
1.1M shares, 4.1% of float, as of Oct 15, 2026.
What sector is TLPH in?
Healthcare, in the Pharmaceuticals industry.

About Talphera

Talphera Inc. is a pharmaceutical company focused on the development and commercialization of therapies for use in medically supervised settings. The Company's nafamostat product candidates include Niyad and LTX-608. Its portfolio consists of nafamostat product candidates and pre-filled syringe product candidates.

HQ: San Mateo, CA12 employeesListed Feb 11, 2011talphera.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology