NASDAQ · PLRXHealthcarePharmaceuticals

Pliant Therapeutics, Inc. Common Stock (PLRX)

$0.8518−1.03%
Close Nov 4, 2026 · split-adjusted
Nov 4, 2026$0.85▼ 47.09% in range
Nov 4, 2025Low $0.84 · High $1.80Nov 4, 2026
What changed · written from our data
As of Nov 4, 2026

Pliant Therapeutics closed at $0.85 on Nov 4, down 1.03%, within 1.5% of its 52-week closing low. Volume of 205.3K shares was 0.54× its 20-day average (below normal).

Split-adjusted performance: -17.3% over one month, -30.7% over six months, -49.0% over one year.

Short interest was 4.6M shares at the Oct 15 settlement, up 9.1% from the prior report (9.6% of float, 10.4 days to cover).

Market cap$52.7M61.9M shares
Revenue · quarter$0.00—
Diluted EPS$-0.36—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range0.84 – 1.80−52.7% from high
Volume205.3K0.54× 20-day avg
Volatility · 60d50.5%Annualised
Short % of float9.6%10.4 days to cover
Net cash$158.1MCash $158.1M
Next earnings—Not scheduled
Split-adjusted performance
1W −4.3%1M −17.3%3M −18.9%6M −30.7%YTD −30.2%1Y −49.0%3Y −93.9%5Y −94.6%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum44
Revenue growth—
Net margin—
Value (low P/E)—
Size31

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short4.6M+9.1% vs prior
Days to cover10.4Settled Oct 15
% of float9.6%
Short vol. 10d37.5%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
PLRXPliant Therapeutics$0.8518−1.03%−30.7%———$52.7M
HOWLWerewolf Therapeutics$1.09+1.87%+67.6%—17.5%—$53.0MCompare
OSTXOS Therapies Incorporated$1.15−0.86%−33.5%———$53.8MCompare
ANVSAnnovis Bio$1.21+11.01%−49.6%———$51.6MCompare
IBIOiBio$0.8000−2.85%−54.8%−100.0%——$51.4MCompare
TLPHTalphera$1.05+0.96%+20.7%———$54.5MCompare
BOLDBoundless Bio$2.40+0.84%+51.9%———$55.5MCompare
ONCYOncolytics Biotech$0.4248+8.92%−53.8%———$55.7MCompare
RFLRafael Holdings$1.07−0.93%−14.4%−30.3%−3760.7%—$55.8MCompare

Quick answers

What does Pliant Therapeutics do?
Pliant Therapeutics Inc is a clinical-stage biopharmaceutical company engaged in the discovery and development of integrin-based therapies. The company operates as a single reportable segment focused on developing and commercializing novel integrin-based treatments.
What is PLRX's market cap?
$52.75M, based on the Nov 4 close of $0.85.
Does Pliant Therapeutics pay a dividend?
No regular cash dividend has been paid in the last year.
How much of PLRX is sold short?
4.6M shares, 9.6% of float, as of Oct 15, 2026.
What sector is PLRX in?
Healthcare, in the Pharmaceuticals industry.

About Pliant Therapeutics

Pliant Therapeutics Inc is a clinical-stage biopharmaceutical company engaged in the discovery and development of integrin-based therapies. The company operates as a single reportable segment focused on developing and commercializing novel integrin-based treatments. Its lead product candidate, PLN-101095, is an oral small molecule targeting integrins for the treatment of solid tumors. The company also advances a pipeline of integrin-based programs across multiple disease areas through its proprietary drug discovery platform.

HQ: South San Francisco, CA49 employeesListed Jun 3, 2020pliantrx.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology