NASDAQ · MNPRHealthcarePharmaceuticals

Monopar Therapeutics Inc. Common Stock (MNPR)

$72.81+4.18%
Close Nov 4, 2026 · split-adjusted
Nov 3, 2026$69.89▼ 16.80% in range
Nov 3, 2025Low $50.12 · High $123.84Nov 3, 2026
What changed · written from our data
As of Nov 4, 2026

Monopar Therapeutics closed at $72.81 on Nov 4, up 4.18%, 41.2% below its 52-week closing high. Volume of 189.7K shares was 1.33× its 20-day average (above normal).

Split-adjusted performance: -8.5% over one month, +14.0% over six months, -13.3% over one year.

Short interest was 1.1M shares at the Oct 15 settlement, up 3.9% from the prior report (23.3% of float, 7.1 days to cover).

Market cap$488.7M6.7M shares
Revenue · quarter$0.00—
Diluted EPS$-0.62—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range50.12 – 123.84−41.2% from high
Volume189.7K1.33× 20-day avg
Volatility · 60d52.6%Annualised
Short % of float23.3%7.1 days to cover
Net cash$134.3MCash $134.3M
Next earnings—Not scheduled
Split-adjusted performance
1W −0.8%1M −8.5%3M −39.4%6M +14.0%YTD +11.5%1Y −13.3%3Y +3504.5%5Y +191.2%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum79
Revenue growth—
Net margin—
Value (low P/E)—
Size60

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short1.1M+3.9% vs prior
Days to cover7.1Settled Oct 15
% of float23.3%
Short vol. 10d53.5%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
MNPRMonopar Therapeutics$72.81+4.18%+14.0%———$488.7M
ARVNArvinas$7.42+4.65%−27.7%+1014.7%67.8%52.2$485.2MCompare
EOLSEvolus$7.47+1.36%+18.2%+21.2%−9.6%—$493.4MCompare
AQSTAquestive Therapeutics$3.80−2.06%−10.2%+38.1%−165.5%—$476.9MCompare
GYREGyre Therapeutics$4.440.00%−44.8%−2.1%−40.1%—$470.8MCompare
CTMXCytomX Therapeutics$2.35+7.80%−43.1%−92.4%−1457.4%—$512.1MCompare
CBIOCrescent Biopharma$13.82+5.82%−23.5%———$513.4MCompare
FTHFaeth Therapeutics$19.99+1.73%————$516.6MCompare
STTKShattuck Labs$5.15−5.85%−22.9%———$516.9MCompare

Quick answers

What does Monopar Therapeutics do?
Monopar Therapeutics Inc is a clinical-stage biopharmaceutical company developing a treatment for Wilson disease and novel radiopharmaceuticals for oncology. Its Wilson disease product candidate is ALXN1840, a late-stage, investigational once-daily, oral medicine.
What is MNPR's market cap?
$488.71M, based on the Nov 4 close of $72.81.
Does Monopar Therapeutics pay a dividend?
No regular cash dividend has been paid in the last year.
How much of MNPR is sold short?
1.1M shares, 23.3% of float, as of Oct 15, 2026.
What sector is MNPR in?
Healthcare, in the Pharmaceuticals industry.

About Monopar Therapeutics

Monopar Therapeutics Inc is a clinical-stage biopharmaceutical company developing a treatment for Wilson disease and novel radiopharmaceuticals for oncology. Its Wilson disease product candidate is ALXN1840, a late-stage, investigational once-daily, oral medicine. The group radiopharmaceutical programs consist of Phase 1-stage MNPR-101-Zr for imaging cancers, and Phase 1a-stage MNPR-101-Lu and late preclinical-stage MNPR-101-Ac for the treatment of cancers that express urokinase plasminogen activator receptor (uPAR). It build drug development pipeline through both in-house efforts and licensing of late preclinical- and clinical-stage therapeutics. The Company operates as a single reportable segment, focusing on the development of clinical and preclinical product candidates.

HQ: Wilmette, IL22 employeesListed Dec 19, 2019monopartx.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology