NASDAQ · CBIOHealthcarePharmaceuticals

Crescent Biopharma, Inc. Common Stock (CBIO)

$13.82+5.82%
Close Nov 4, 2026 · split-adjusted
Nov 2, 2026$12.91▲ 4.53% in range
Nov 3, 2025Low $8.94 · High $26.98Nov 2, 2026
What changed · written from our data
As of Nov 4, 2026

Crescent Biopharma closed at $13.82 on Nov 4, up 5.82%, 48.8% below its 52-week closing high. Volume of 172.9K shares was 0.60× its 20-day average (below normal).

Split-adjusted performance: +1.8% over one month, -23.5% over six months, +11.9% over one year.

Short interest was 4.4M shares at the Oct 15 settlement, down 7.5% from the prior report (21.2% of float, 12.7 days to cover).

Market cap$513.4M37.1M shares
Revenue · quarter$0.00—
Diluted EPS$-0.74—
P/E · TTM—P/S 43.2×
Net margin—
Dividend yieldNone
52-week range8.94 – 26.98−48.8% from high
Volume172.9K0.60× 20-day avg
Volatility · 60d69.7%Annualised
Short % of float21.2%12.7 days to cover
Net cash$171.6MCash $171.6M
Next earnings—Not scheduled
Split-adjusted performance
1W +2.4%1M +1.8%3M −15.9%6M −23.5%YTD +16.5%1Y +11.9%3Y +80.2%5Y −71.0%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum53
Revenue growth—
Net margin—
Value (low P/E)—
Size61

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short4.4M−7.5% vs prior
Days to cover12.7Settled Oct 15
% of float21.2%
Short vol. 10d62.1%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
CBIOCrescent Biopharma$13.82+5.82%−23.5%———$513.4M
CTMXCytomX Therapeutics$2.35+7.80%−43.1%−92.4%−1457.4%—$512.1MCompare
FTHFaeth Therapeutics$19.99+1.73%————$516.6MCompare
STTKShattuck Labs$5.15−5.85%−22.9%———$516.9MCompare
CAPRCapricor Therapeutics$8.92+8.25%−74.1%———$518.6MCompare
EOLSEvolus$7.47+1.36%+18.2%+21.2%−9.6%—$493.4MCompare
OVIDOvid Therapeutics$2.74+14.17%−1.4%−88.3%−2047.6%—$535.1MCompare
CLYMClimb Bio$9.33−4.31%−23.6%———$535.9MCompare
MNPRMonopar Therapeutics$72.81+4.18%+14.0%———$488.7MCompare

Quick answers

What does Crescent Biopharma do?
Crescent Biopharma Inc is a biopharmaceutical company developing novel therapeutics to treat solid tumors, led by CR-001, a proprietary anti-PD-1/anti-VEGF bispecific antibody. Crescent's pipeline product CR-001 has the potential to deliver improved clinical efficacy and safety over pembrolizumab.
What is CBIO's market cap?
$513.37M, based on the Nov 4 close of $13.82.
Does Crescent Biopharma pay a dividend?
No regular cash dividend has been paid in the last year.
How much of CBIO is sold short?
4.4M shares, 21.2% of float, as of Oct 15, 2026.
What sector is CBIO in?
Healthcare, in the Pharmaceuticals industry.

About Crescent Biopharma

Crescent Biopharma Inc is a biopharmaceutical company developing novel therapeutics to treat solid tumors, led by CR-001, a proprietary anti-PD-1/anti-VEGF bispecific antibody. Crescent's pipeline product CR-001 has the potential to deliver improved clinical efficacy and safety over pembrolizumab. CR-001 is a new molecular entity designed to replicate the functional properties of ivonescimab, a cooperative bispecific anti-PD-1/anti-VEGF antibody in development by Akeso Biopharma and Summit Therapeutics that delivered improved efficacy in a head-to-head Phase 3 clinical trial versus Keytruda in non-small cell lung cancer. The company focuses on advancing its second and third programs, CR-002 and CR-003, which are antibody drug conjugates (ADCs) against validated oncology targets.

HQ: Waltham, MA44 employeesListed Jun 16, 2025crescentbiopharma.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology