NASDAQ · GYREHealthcarePharmaceuticals

Gyre Therapeutics, Inc. Common Stock (GYRE)

$4.440.00%
Close Nov 4, 2026 · split-adjusted
Nov 4, 2026$4.44▼ 38.76% in range
Nov 4, 2025Low $4.44 · High $8.76Nov 4, 2026
What changed · written from our data
As of Nov 4, 2026

Gyre Therapeutics closed at $4.44 on Nov 4, unchanged, within 0.0% of its 52-week closing low. Volume of 256.2K shares was 1.65× its 20-day average (above normal).

Split-adjusted performance: -37.3% over one month, -44.8% over six months, -39.7% over one year.

In the quarter ended Jun 30, 2026, revenue was $29.11M, down 2.1% from a year earlier, with a net margin of -40.1%.

Short interest was 1.9M shares at the Oct 15 settlement (11.5% of float, 16.3 days to cover).

Market cap$470.8M106.0M shares
Revenue · quarter$29.1M−2.1% YoY
Diluted EPS$-0.12—
P/E · TTM—P/S 3.9×
Net margin-40.1%Gross 92.4%
Dividend yieldNone$0.24 last paid
52-week range4.44 – 8.76−49.3% from high
Volume256.2K1.65× 20-day avg
Volatility · 60d88.3%Annualised
Short % of float11.5%16.3 days to cover
Net cash$74.8MCash $74.8M
Next earnings—Not scheduled
Split-adjusted performance
1W −37.4%1M −37.3%3M −30.6%6M −44.8%YTD −37.1%1Y −39.7%3Y —5Y —

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum29
Revenue growth38
Net margin48
Value (low P/E)—
Size60

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short1.9M+0.5% vs prior
Days to cover16.3Settled Oct 15
% of float11.5%
Short vol. 10d66.5%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
GYREGyre Therapeutics$4.440.00%−44.8%−2.1%−40.1%—$470.8M
AQSTAquestive Therapeutics$3.80−2.06%−10.2%+38.1%−165.5%—$476.9MCompare
PHATPhathom Pharmaceuticals$5.68−1.05%−55.2%+71.1%−16.4%—$461.7MCompare
ARVNArvinas$7.42+4.65%−27.7%+1014.7%67.8%52.2$485.2MCompare
MNPRMonopar Therapeutics$72.81+4.18%+14.0%———$488.7MCompare
EOLSEvolus$7.47+1.36%+18.2%+21.2%−9.6%—$493.4MCompare
RLMDRelmada Therapeutics$4.17−2.34%−46.9%———$444.8MCompare
CRMDCorMedix$5.66+1.80%−29.7%+156.5%25.5%2.4$441.2MCompare
INDPIndaptus Therapeutics$3.30+1.85%+61.0%———$439.7MCompare

Quick answers

What does Gyre Therapeutics do?
Gyre Therapeutics Inc is a commercial-stage biopharmaceutical company focused on the development and commercialization of small-molecule therapies for the treatment of organ fibrosis and inflammatory diseases. The company's commercial-stage products include ETUARY, Avatrombopag, and Nintedanib.
What is GYRE's market cap?
$470.79M, based on the Nov 4 close of $4.44.
Does Gyre Therapeutics pay a dividend?
No regular cash dividend has been paid in the last year.
How much of GYRE is sold short?
1.9M shares, 11.5% of float, as of Oct 15, 2026.
What sector is GYRE in?
Healthcare, in the Pharmaceuticals industry.

About Gyre Therapeutics

Gyre Therapeutics Inc is a commercial-stage biopharmaceutical company focused on the development and commercialization of small-molecule therapies for the treatment of organ fibrosis and inflammatory diseases. The company's commercial-stage products include ETUARY, Avatrombopag, and Nintedanib. In addition, it is focused on the development and commercialization of Hydronidone (F351) for the treatment of Metabolic Dysfunction Associated Steatohepatitis (MASH-associated liver fibrosis (MASH fibrosis). Gyre is also advancing a diverse pipeline of different drug candidates in China, including F573, F528, and F230. The company's reportable segments are Gyre Pharmaceuticals, which derives maximum revenue from the sale of ETUARY and certain generic drugs in the PRC, Gyre, and Other.

HQ: San Diego, CA618 employeesListed Oct 31, 2023gyretx.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology