NASDAQ · XENEHealthcarePharmaceuticals

Xenon Pharmaceuticals Inc (XENE)

$39.19+2.51%
Close Nov 4, 2026 · split-adjusted
Nov 3, 2026$38.23▼ 7.03% in range
Nov 3, 2025Low $33.49 · High $70.96Nov 3, 2026
What changed · written from our data
As of Nov 4, 2026

Xenon Pharmaceuticals closed at $39.19 on Nov 4, up 2.51%, 44.8% below its 52-week closing high. Volume of 1.7M shares was 1.21× its 20-day average (close to normal).

Split-adjusted performance: +7.2% over one month, -33.1% over six months, -4.7% over one year.

Short interest was 7.3M shares at the Oct 15 settlement, up 21.6% from the prior report (8.1% of float, 4.0 days to cover).

Market cap$3.80B96.8M shares
Revenue · quarter$0.00—
Diluted EPS$-1.11—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range33.49 – 70.96−44.8% from high
Volume1.7M1.21× 20-day avg
Volatility · 60d82.7%Annualised
Short % of float8.1%4.0 days to cover
Net cash$930.7MCash $930.7M
Next earnings—Not scheduled
Split-adjusted performance
1W +7.8%1M +7.2%3M −39.3%6M −33.1%YTD −12.6%1Y −4.7%3Y +24.4%5Y +30.2%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum41
Revenue growth—
Net margin—
Value (low P/E)—
Size88

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short7.3M+21.6% vs prior
Days to cover4.0Settled Oct 15
% of float8.1%
Short vol. 10d65.1%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
XENEXenon Pharmaceuticals$39.19+2.51%−33.1%———$3.80B
PBLSParabilis Medicines$30.36+3.79%——−45239.9%—$3.75BCompare
ACADAcadia Pharmaceuticals$21.47+4.38%0.0%+16.4%10.2%9.7$3.70BCompare
IRONDisc Medicine$83.28+2.61%+21.3%———$3.70BCompare
AMLXAmylyx Pharmaceuticals$29.40+0.68%+83.1%———$3.69BCompare
TNGXTango Therapeutics$23.18+0.04%−1.9%−100.0%——$3.91BCompare
OGNOrganon &$13.83−0.14%+3.1%−1.7%10.4%17.1$3.63BCompare
ABCLAbCellera Biologics$12.28+0.82%+143.7%−76.3%−1368.6%—$3.98BCompare
VKTXViking Therapeutics$27.97+7.21%−13.4%———$3.57BCompare

Quick answers

What does Xenon Pharmaceuticals do?
Xenon Pharmaceuticals Inc is a neuroscience-focused biopharmaceutical company committed to improving the lives of people living with neurological and psychiatric disorders. It is advancing a novel product pipeline to address areas of high unmet medical need, including epilepsy and depression.
What is XENE's market cap?
$3.80B, based on the Nov 4 close of $39.19.
Does Xenon Pharmaceuticals pay a dividend?
No regular cash dividend has been paid in the last year.
How much of XENE is sold short?
7.3M shares, 8.1% of float, as of Oct 15, 2026.
What sector is XENE in?
Healthcare, in the Pharmaceuticals industry.

About Xenon Pharmaceuticals

Xenon Pharmaceuticals Inc is a neuroscience-focused biopharmaceutical company committed to improving the lives of people living with neurological and psychiatric disorders. It is advancing a novel product pipeline to address areas of high unmet medical need, including epilepsy and depression. The product candidates of the group include XEN1101, NBI-921352, and XEN496 for Epilepsy and Nav1.7 oral inhibitors for Pain.

HQ: Burnaby, 370 employeesListed Nov 5, 2014xenon-pharma.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology