NASDAQ · AMLXHealthcarePharmaceuticals

Amylyx Pharmaceuticals, Inc. Common Stock (AMLX)

$29.40+0.68%
Close Nov 4, 2026 · split-adjusted
Nov 3, 2026$29.20▲ 114.71% in range
Nov 3, 2025Low $11.38 · High $39.66Nov 3, 2026
What changed · written from our data
As of Nov 4, 2026

Amylyx Pharmaceuticals closed at $29.40 on Nov 4, up 0.68%, 25.9% below its 52-week closing high. Volume of 1.6M shares was 1.20× its 20-day average (close to normal).

Split-adjusted performance: +4.9% over one month, +83.1% over six months, +116.2% over one year.

Short interest was 13.2M shares at the Oct 15 settlement, up 4.6% from the prior report (13.7% of float, 9.9 days to cover).

Market cap$3.69B125.5M shares
Revenue · quarter$0.00—
Diluted EPS$-0.39—
P/E · TTM—
Net margin—
Dividend yieldNone$0.4197 last paid
52-week range11.38 – 39.66−25.9% from high
Volume1.6M1.20× 20-day avg
Volatility · 60d112.2%Annualised
Short % of float13.7%9.9 days to cover
Net cash$250.8MCash $250.8M
Next earnings—Not scheduled
Split-adjusted performance
1W +4.7%1M +4.9%3M +21.5%6M +83.1%YTD +143.4%1Y +116.2%3Y +86.6%5Y —

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum98
Revenue growth—
Net margin—
Value (low P/E)—
Size87

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short13.2M+4.6% vs prior
Days to cover9.9Settled Oct 15
% of float13.7%
Short vol. 10d51.7%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
AMLXAmylyx Pharmaceuticals$29.40+0.68%+83.1%———$3.69B
IRONDisc Medicine$83.28+2.61%+21.3%———$3.70BCompare
ACADAcadia Pharmaceuticals$21.47+4.38%0.0%+16.4%10.2%9.7$3.70BCompare
OGNOrganon &$13.83−0.14%+3.1%−1.7%10.4%17.1$3.63BCompare
PBLSParabilis Medicines$30.36+3.79%——−45239.9%—$3.75BCompare
XENEXenon Pharmaceuticals$39.19+2.51%−33.1%———$3.80BCompare
VKTXViking Therapeutics$27.97+7.21%−13.4%———$3.57BCompare
TNGXTango Therapeutics$23.18+0.04%−1.9%−100.0%——$3.91BCompare
DYNDyne Therapeutics$18.54+2.71%−1.6%———$3.46BCompare

Quick answers

What does Amylyx Pharmaceuticals do?
Amylyx Pharmaceuticals Inc is a clinical-stage pharmaceutical company focused on developing novel therapies for communities with high unmet medical needs. The company has preclinical and clinical development programs in endocrine conditions and neurodegenerative diseases.
What is AMLX's market cap?
$3.69B, based on the Nov 4 close of $29.40.
Does Amylyx Pharmaceuticals pay a dividend?
No regular cash dividend has been paid in the last year.
How much of AMLX is sold short?
13.2M shares, 13.7% of float, as of Oct 15, 2026.
What sector is AMLX in?
Healthcare, in the Pharmaceuticals industry.

About Amylyx Pharmaceuticals

Amylyx Pharmaceuticals Inc is a clinical-stage pharmaceutical company focused on developing novel therapies for communities with high unmet medical needs. The company has preclinical and clinical development programs in endocrine conditions and neurodegenerative diseases. Its pipeline includes investigational therapies matched with diseases based on mechanistic rationale, clinical outcomes, biomarkers, and preclinical data. The company is currently developing avexitide for Post-Bariatric Hypoglycemia, AMX0035 for Wolfram Syndrome, AMX0114 for Amyotrophic Lateral Sclerosis, and AMX0318 for Post-Bariatric Hypoglycemia and other rare diseases.

HQ: Cambridge, MA136 employeesListed Jan 7, 2022amylyx.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology