NASDAQ · TPSTHealthcarePharmaceuticals

Tempest Therapeutics, Inc. Common Stock (TPST)

$0.4633−1.13%
Close Nov 4, 2026 · split-adjusted
Nov 3, 2026$0.46▼ 90.73% in range
Nov 3, 2025Low $0.46 · High $5.01Nov 3, 2026
What changed · written from our data
As of Nov 4, 2026

Tempest Therapeutics closed at $0.46 on Nov 4, down 1.13%, within 0.0% of its 52-week closing low. Volume of 108.5K shares was 0.71× its 20-day average (below normal).

Split-adjusted performance: -41.2% over one month, -77.1% over six months, -90.8% over one year.

Short interest was 312.9K shares at the Oct 15 settlement, down 48.6% from the prior report (3.1% of float, 1.0 days to cover).

Market cap$9.3M20.0M shares
Revenue · quarter$0.00—
Diluted EPS$-0.34—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range0.46 – 5.01−90.8% from high
Volume108.5K0.71× 20-day avg
Volatility · 60d152.2%Annualised
Short % of float3.1%1.0 days to cover
Net cash$779.0KCash $779.0K
Next earnings—Not scheduled
Split-adjusted performance
1W −14.2%1M −41.2%3M −48.7%6M −77.1%YTD −67.7%1Y −90.8%3Y −98.2%5Y −99.4%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum9
Revenue growth—
Net margin—
Value (low P/E)—
Size15

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short312.9K−48.6% vs prior
Days to cover1.0Settled Oct 15
% of float3.1%
Short vol. 10d51.7%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
TPSTTempest Therapeutics$0.4633−1.13%−77.1%———$9.3M
CALCCalciMedica$1.35−8.50%−56.8%———$9.2MCompare
CURXCuranex Pharmaceuticals$5.80−6.30%−17.7%———$9.1MCompare
ACTUActuate Therapeutics$0.3699+5.69%−87.6%———$8.9MCompare
MTVAMetaVia$1.34+6.35%−4.3%———$8.8MCompare
BFRGBullfrog AI Holdings$0.5263+0.59%−25.4%+547.6%−636.8%—$9.8MCompare
LTRNLantern Pharma$0.5866−2.61%−72.6%———$8.8MCompare
GTBPGT Biopharma$4.84−8.16%−51.9%———$8.7MCompare
TOVXTheriva Biologics$0.1900+4.40%−50.3%———$8.7MCompare

Quick answers

What does Tempest Therapeutics do?
Tempest Therapeutics Inc is a late-stage develpment biotechnology company developing small molecule therapeutics to treat cancer through mechanisms that directly kill tumor cells and activate tumor-specific immunity. Its clinical-stage therapeutic product candidates are TPST-1120 and TPST-1495 which are clinical-stage molecules designed to inhibit their respective targets.
What is TPST's market cap?
$9.26M, based on the Nov 4 close of $0.46.
Does Tempest Therapeutics pay a dividend?
No regular cash dividend has been paid in the last year.
How much of TPST is sold short?
312.9K shares, 3.1% of float, as of Oct 15, 2026.
What sector is TPST in?
Healthcare, in the Pharmaceuticals industry.

About Tempest Therapeutics

Tempest Therapeutics Inc is a late-stage develpment biotechnology company developing small molecule therapeutics to treat cancer through mechanisms that directly kill tumor cells and activate tumor-specific immunity. Its clinical-stage therapeutic product candidates are TPST-1120 and TPST-1495 which are clinical-stage molecules designed to inhibit their respective targets. Company's small-molecule product candidate, amezalpat (previously known as TPST-1120), has completed a Phase 2 study in first-line hepatocellular carcinoma and the second small-molecule product candidate is TPST-1495, plans to initiate a Phase 2 study for in familial adenomatous polyposis.

HQ: Brisbane, CA4 employeesListed Jun 28, 2021tempesttx.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology