NASDAQ · ACTUHealthcarePharmaceuticals

Actuate Therapeutics, Inc. Common stock (ACTU)

$0.3699+5.69%
Close Nov 4, 2026 · split-adjusted
Nov 4, 2026$0.37▼ 94.24% in range
Nov 4, 2025Low $0.34 · High $7.63Nov 4, 2026
What changed · written from our data
As of Nov 4, 2026

Actuate Therapeutics closed at $0.37 on Nov 4, up 5.69%, 95.2% below its 52-week closing high. Volume of 303.7K shares was 0.55× its 20-day average (below normal).

Split-adjusted performance: -54.4% over one month, -87.6% over six months, -94.5% over one year.

Short interest was 1.9M shares at the Oct 15 settlement, up 40.4% from the prior report (19.2% of float, 4.7 days to cover).

Market cap$8.9M24.0M shares
Revenue · quarter$0.00—
Diluted EPS$-0.20—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range0.34 – 7.63−95.2% from high
Volume303.7K0.55× 20-day avg
Volatility · 60d161.7%Annualised
Short % of float19.2%4.7 days to cover
Net cash$4.4MCash $4.4M
Next earnings—Not scheduled
Split-adjusted performance
1W −3.5%1M −54.4%3M −69.9%6M −87.6%YTD −94.0%1Y −94.5%3Y —5Y —

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum4
Revenue growth—
Net margin—
Value (low P/E)—
Size14

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short1.9M+40.4% vs prior
Days to cover4.7Settled Oct 15
% of float19.2%
Short vol. 10d48.0%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
ACTUActuate Therapeutics$0.3699+5.69%−87.6%———$8.9M
MTVAMetaVia$1.34+6.35%−4.3%———$8.8MCompare
LTRNLantern Pharma$0.5866−2.61%−72.6%———$8.8MCompare
GTBPGT Biopharma$4.84−8.16%−51.9%———$8.7MCompare
TOVXTheriva Biologics$0.1900+4.40%−50.3%———$8.7MCompare
CURXCuranex Pharmaceuticals$5.80−6.30%−17.7%———$9.1MCompare
MBRXMoleculin Biotech$8.46+1.93%−82.9%———$8.6MCompare
CALCCalciMedica$1.35−8.50%−56.8%———$9.2MCompare
LEXXLexaria Bioscience$4.07+0.99%−59.8%−100.0%——$8.6MCompare

Quick answers

What does Actuate Therapeutics do?
Actuate Therapeutics Inc is a clinical stage biopharmaceutical company focused on developing therapies for the treatment of high impact, difficult to treat cancers through the inhibition of glycogen synthase kinase-3 (GSK-3). It is developing elraglusib (formerly 9-ING-41), a small molecule that is designed to enter cancer cells and block the function of the enzyme GSK-3B, a master regulator of complex biological signaling cascades, including those mediated by oncogenes, that lead to tumor cell survival, growth, migration, and invasion.
What is ACTU's market cap?
$8.88M, based on the Nov 4 close of $0.37.
Does Actuate Therapeutics pay a dividend?
No regular cash dividend has been paid in the last year.
How much of ACTU is sold short?
1.9M shares, 19.2% of float, as of Oct 15, 2026.
What sector is ACTU in?
Healthcare, in the Pharmaceuticals industry.

About Actuate Therapeutics

Actuate Therapeutics Inc is a clinical stage biopharmaceutical company focused on developing therapies for the treatment of high impact, difficult to treat cancers through the inhibition of glycogen synthase kinase-3 (GSK-3). It is developing elraglusib (formerly 9-ING-41), a small molecule that is designed to enter cancer cells and block the function of the enzyme GSK-3B, a master regulator of complex biological signaling cascades, including those mediated by oncogenes, that lead to tumor cell survival, growth, migration, and invasion.

HQ: Fort Worth, TX12 employeesListed Aug 13, 2024actuatetherapeutics.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology