NASDAQ · PVLAHealthcarePharmaceuticals

Palvella Therapeutics, Inc. Common Stock (PVLA)

$162.28+6.11%
Close Nov 4, 2026 · split-adjusted
Nov 3, 2026$152.93▲ 99.02% in range
Nov 3, 2025Low $75.06 · High $158.13Nov 3, 2026
What changed · written from our data
As of Nov 4, 2026

Palvella Therapeutics closed at $162.28 on Nov 4, up 6.11% — matching its 52-week closing high. Volume of 407.4K shares was 1.71× its 20-day average (above normal).

Split-adjusted performance: +26.8% over one month, +24.7% over six months, +111.2% over one year.

Short interest was 2.4M shares at the Oct 15 settlement, down 4.6% from the prior report (21.7% of float, 9.8 days to cover).

Market cap$2.34B14.4M shares
Revenue · quarter$0.00—
Diluted EPS$-1.52—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range75.06 – 162.280.0% from high
Volume407.4K1.71× 20-day avg
Volatility · 60d48.6%Annualised
Short % of float21.7%9.8 days to cover
Net cash$250.6MCash $250.6M
Next earnings—Not scheduled
Split-adjusted performance
1W +10.0%1M +26.8%3M +4.7%6M +24.7%YTD +55.0%1Y +111.2%3Y —5Y —

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum84
Revenue growth—
Net margin—
Value (low P/E)—
Size84

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short2.4M−4.6% vs prior
Days to cover9.8Settled Oct 15
% of float21.7%
Short vol. 10d72.2%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
PVLAPalvella Therapeutics$162.28+6.11%+24.7%———$2.34B
VERAVera Therapeutics$31.97+4.10%−12.6%———$2.30BCompare
IMNMImmunome$19.52−3.89%−16.1%−100.0%——$2.30BCompare
BHVNBiohaven$15.24−2.37%+51.8%———$2.30BCompare
AUPHAurinia Pharmaceuticals$17.11+3.32%+5.3%+13.9%37.9%7.3$2.29BCompare
SEPNSepterna$47.88+9.57%+93.8%+22375.6%−48.7%—$2.23BCompare
TRLVTrulieve Cannabis$11.60+0.52%——−149.8%—$2.23BCompare
ZYMEZymeworks$30.94+2.69%+12.1%−90.6%−980.8%—$2.22BCompare
RCUSArcus Biosciences$19.31+2.12%−25.7%−74.4%−222.0%—$2.46BCompare

Quick answers

What does Palvella Therapeutics do?
Palvella Therapeutics Inc is a clinical-stage biopharmaceutical company whose vision is to become the rare disease biopharmaceutical company focused on developing and commercializing novel therapies to treat patients suffering from serious, rare skin diseases and vascular malformations for which there are no FDA-approved therapies. Its product candidate, QTORIN 3.9% rapamycin anhydrous gel, is currently in clinical development for microcystic lymphatic malformations and cutaneous venous malformations.
What is PVLA's market cap?
$2.34B, based on the Nov 4 close of $162.28.
Does Palvella Therapeutics pay a dividend?
No regular cash dividend has been paid in the last year.
How much of PVLA is sold short?
2.4M shares, 21.7% of float, as of Oct 15, 2026.
What sector is PVLA in?
Healthcare, in the Pharmaceuticals industry.

About Palvella Therapeutics

Palvella Therapeutics Inc is a clinical-stage biopharmaceutical company whose vision is to become the rare disease biopharmaceutical company focused on developing and commercializing novel therapies to treat patients suffering from serious, rare skin diseases and vascular malformations for which there are no FDA-approved therapies. Its product candidate, QTORIN 3.9% rapamycin anhydrous gel, is currently in clinical development for microcystic lymphatic malformations and cutaneous venous malformations. It operates in single segment.

HQ: Wayne, PA29 employeesListed Dec 16, 2024palvellatx.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology