NASDAQ · ZYMEHealthcarePharmaceuticals

Zymeworks Inc. (ZYME)

$30.94+2.69%
Close Nov 4, 2026 · split-adjusted
Nov 4, 2026$30.94▲ 70.37% in range
Nov 4, 2025Low $16.46 · High $31.05Nov 4, 2026
What changed · written from our data
As of Nov 4, 2026

Zymeworks closed at $30.94 on Nov 4, up 2.69%, 0.4% below its 52-week closing high. Volume of 1.0M shares was 0.72× its 20-day average (below normal).

Split-adjusted performance: +20.6% over one month, +12.1% over six months, +63.8% over one year.

In the quarter ended Jun 30, 2026, revenue was $4.59M, down 90.6% from a year earlier, with a net margin of -980.8%.

Short interest was 5.6M shares at the Oct 15 settlement, up 5.4% from the prior report (12.5% of float, 4.4 days to cover).

Market cap$2.22B71.9M shares
Revenue · quarter$4.6M−90.6% YoY
Diluted EPS$-0.62−2166.7% YoY
P/E · TTM—P/S 59.9×
Net margin-980.8%Gross 100.0%
Dividend yieldNone
52-week range16.46 – 31.05−0.4% from high
Volume1.0M0.72× 20-day avg
Volatility · 60d47.0%Annualised
Short % of float12.5%4.4 days to cover
Net cash$270.7MCash $270.7M
Next earnings—Not scheduled
Split-adjusted performance
1W +7.1%1M +20.6%3M +33.8%6M +12.1%YTD +17.5%1Y +63.8%3Y +342.6%5Y +36.5%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum77
Revenue growth12
Net margin23
Value (low P/E)—
Size82

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short5.6M+5.4% vs prior
Days to cover4.4Settled Oct 15
% of float12.5%
Short vol. 10d51.1%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
ZYMEZymeworks$30.94+2.69%+12.1%−90.6%−980.8%—$2.22B
TRLVTrulieve Cannabis$11.60+0.52%——−149.8%—$2.23BCompare
SEPNSepterna$47.88+9.57%+93.8%+22375.6%−48.7%—$2.23BCompare
PRGOPERRIGO$15.83+0.83%+29.1%−3.2%7.3%—$2.20BCompare
AUPHAurinia Pharmaceuticals$17.11+3.32%+5.3%+13.9%37.9%7.3$2.29BCompare
BHVNBiohaven$15.24−2.37%+51.8%———$2.30BCompare
IMNMImmunome$19.52−3.89%−16.1%−100.0%——$2.30BCompare
VERAVera Therapeutics$31.97+4.10%−12.6%———$2.30BCompare
SDGRSchrodinger$28.52+4.93%+119.7%+7.5%10.1%—$2.13BCompare

Quick answers

What does Zymeworks do?
Zymeworks Inc is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation multifunctional biotherapeutics. Its suite of therapeutic platforms and its fully integrated drug development engine enables precise engineering of differentiated therapeutic product candidates.
What is ZYME's market cap?
$2.22B, based on the Nov 4 close of $30.94.
Does Zymeworks pay a dividend?
No regular cash dividend has been paid in the last year.
How much of ZYME is sold short?
5.6M shares, 12.5% of float, as of Oct 15, 2026.
What sector is ZYME in?
Healthcare, in the Pharmaceuticals industry.

About Zymeworks

Zymeworks Inc is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation multifunctional biotherapeutics. Its suite of therapeutic platforms and its fully integrated drug development engine enables precise engineering of differentiated therapeutic product candidates. Its clinical candidate, zanidatamab, is a novel HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. It is also advancing a deep preclinical pipeline in oncology and other therapeutic areas.

HQ: Middletown, DE264 employeesListed Apr 28, 2017zymeworks.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology