NASDAQ · MBXHealthcarePharmaceuticals

MBX Biosciences, Inc. Common Stock (MBX)

$52.48−4.58%
Close Nov 4, 2026 · split-adjusted
Oct 30, 2026$55.87▲ 171.08% in range
Nov 3, 2025Low $20.61 · High $70.70Oct 30, 2026
What changed · written from our data
As of Nov 4, 2026

MBX Biosciences closed at $52.48 on Nov 4, down 4.58%, 25.8% below its 52-week closing high. Volume of 425.5K shares was 0.75× its 20-day average (below normal).

Split-adjusted performance: -7.8% over one month, +63.4% over six months, +154.6% over one year.

Short interest was 4.4M shares at the Oct 15 settlement (15.0% of float, 7.5 days to cover).

Market cap$2.53B48.2M shares
Revenue · quarter——
Diluted EPS——
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range20.61 – 70.70−25.8% from high
Volume425.5K0.75× 20-day avg
Volatility · 60d48.5%Annualised
Short % of float15.0%7.5 days to cover
Net cash—
Next earnings—Not scheduled
Split-adjusted performance
1W −3.1%1M −7.8%3M −21.8%6M +63.4%YTD +66.4%1Y +154.6%3Y —5Y —

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum95
Revenue growth—
Net margin—
Value (low P/E)—
Size85

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short4.4M−1.0% vs prior
Days to cover7.5Settled Oct 15
% of float15.0%
Short vol. 10d57.6%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
MBXMBX Biosciences$52.48−4.58%+63.4%———$2.53B
PBHPrestige Consumer Healthcare$53.28+7.55%−1.9%+6.5%11.0%14.7$2.52BCompare
NAMSNewAmsterdam Pharma Company N.V$20.93+5.18%−32.5%−80.7%−1732.9%—$2.50BCompare
RCUSArcus Biosciences$19.31+2.12%−25.7%−74.4%−222.0%—$2.46BCompare
XNCRXencor$35.03+14.33%+169.3%+17.5%−42.4%—$2.60BCompare
PVLAPalvella Therapeutics$162.28+6.11%+24.7%———$2.34BCompare
VERAVera Therapeutics$31.97+4.10%−12.6%———$2.30BCompare
IMNMImmunome$19.52−3.89%−16.1%−100.0%——$2.30BCompare
BHVNBiohaven$15.24−2.37%+51.8%———$2.30BCompare

Quick answers

What does MBX Biosciences do?
MBX Biosciences Inc is a clinical stage biopharmaceutical company focused on the discovery and development of novel precision peptide therapies for the treatment of endocrine and metabolic disorders. The company designed its proprietary Precision Endocrine Peptide, or PEP, platform to overcome the key limitations of unmodified and modified peptide therapies to improve clinical outcomes and simplify disease management for patients.
What is MBX's market cap?
$2.53B, based on the Nov 4 close of $52.48.
How much of MBX is sold short?
4.4M shares, 15.0% of float, as of Oct 15, 2026.
What sector is MBX in?
Healthcare, in the Pharmaceuticals industry.

About MBX Biosciences

MBX Biosciences Inc is a clinical stage biopharmaceutical company focused on the discovery and development of novel precision peptide therapies for the treatment of endocrine and metabolic disorders. The company designed its proprietary Precision Endocrine Peptide, or PEP, platform to overcome the key limitations of unmodified and modified peptide therapies to improve clinical outcomes and simplify disease management for patients. Its PEPs are selectively engineered to have optimized pharmaceutical properties, including extended time-action profiles and consistent drug concentrations with low peak-to-trough concentration ratios, consistent exposure to target tissues, and less frequent dosing. Its product candidates include canvuparatide (MBX 2109), imapextide (MBX 1416), and MBX 4291.

HQ: Carmel, IN63 employeesListed Sep 13, 2024mbxbio.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology