NASDAQ · DFTXHealthcarePharmaceuticals

Definium Therapeutics, Inc. Common Shares (DFTX)

$32.70−2.13%
Close Nov 4, 2026 · split-adjusted
Nov 4, 2026$32.70▲ 112.61% in range
Jan 15, 2026Low $15.05 · High $48.45Nov 4, 2026
What changed · written from our data
As of Nov 4, 2026

Definium Therapeutics, Inc. Common Shares closed at $32.70 on Nov 4, down 2.13%, 32.5% below its highest close since Jan 15. Volume of 1.4M shares was 0.74× its 20-day average (below normal).

Split-adjusted performance: -8.2% over one month, +39.6% over six months.

Short interest was 10.0M shares at the Oct 15 settlement, down 11.5% from the prior report (7.6% of float, 4.9 days to cover).

Market cap$4.39B134.4M shares
Revenue · quarter$0.00—
Diluted EPS$-1.44—
P/E · TTM—
Net margin—
Dividend yieldNone
Range since Jan 1515.05 – 48.45−32.5% from high
Volume1.4M0.74× 20-day avg
Volatility · 60d56.9%Annualised
Short % of float7.6%4.9 days to cover
Net cash$1.05BCash $1.08B
Next earnings—Not scheduled
Split-adjusted performance
1W −14.2%1M −8.2%3M −29.1%6M +39.6%YTD —1Y —3Y —5Y —

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum90
Revenue growth—
Net margin—
Value (low P/E)—
Size89

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short10.0M−11.5% vs prior
Days to cover4.9Settled Oct 15
% of float7.6%
Short vol. 10d68.2%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
DFTXDefinium Therapeutics$32.70−2.13%+39.6%———$4.39B
ARQTArcutis Biotherapeutics$34.05+6.41%+40.9%+59.3%11.6%150.1$4.28BCompare
LQDALiquidia$47.38+12.27%+12.4%+1842.7%43.5%30.6$4.24BCompare
EWTXEdgewise Therapeutics$37.53−0.40%+1.5%———$4.08BCompare
DNTHDianthus Therapeutics$85.81+3.76%−5.1%+294.3%−6598.6%—$4.80BCompare
ABCLAbCellera Biologics$12.28+0.82%+143.7%−76.3%−1368.6%—$3.98BCompare
TNGXTango Therapeutics$23.18+0.04%−1.9%−100.0%——$3.91BCompare
TVTXTravere Therapeutics$52.42+6.09%+17.1%+36.2%−23.3%—$4.94BCompare
XENEXenon Pharmaceuticals$39.19+2.51%−33.1%———$3.80BCompare

Quick answers

What does Definium Therapeutics, Inc. Common Shares do?
Definium Therapeutics Inc is developing inventive, next-generation therapeutics intended to solve the underlying causes of psychiatric and neurological disorders and offer patients long-term remission rather than transient symptom reduction. Its late-stage pipeline includes four Phase 3 trials-two each for GAD and MDD-anchored by its candidate, DT120 ODT, which has received FDA Breakthrough Therapy Designation for GAD.
What is DFTX's market cap?
$4.39B, based on the Nov 4 close of $32.70.
Does Definium Therapeutics, Inc. Common Shares pay a dividend?
No regular cash dividend has been paid in the last year.
How much of DFTX is sold short?
10.0M shares, 7.6% of float, as of Oct 15, 2026.
What sector is DFTX in?
Healthcare, in the Pharmaceuticals industry.

About Definium Therapeutics

Definium Therapeutics Inc is developing inventive, next-generation therapeutics intended to solve the underlying causes of psychiatric and neurological disorders and offer patients long-term remission rather than transient symptom reduction. Its late-stage pipeline includes four Phase 3 trials-two each for GAD and MDD-anchored by its candidate, DT120 ODT, which has received FDA Breakthrough Therapy Designation for GAD. In parallel, the Company is advancing its commercial and operational readiness to support a care model and prepare for the potential launch of DT120 ODT, if approved and marketed. The company operates in one reportable segment relating to the research and development of the company's neurological drug development platform.

HQ: New York, NY106 employeesListed Mar 3, 2020definiumtx.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology