NASDAQ · AXSMHealthcarePharmaceuticals

Axsome Therapeutics, Inc (AXSM)

$137.00−1.87%
Close Nov 4, 2026 · split-adjusted
Nov 3, 2026$139.61▲ 2.84% in range
Nov 3, 2025Low $134.93 · High $255.17Nov 3, 2026
What changed · written from our data
As of Nov 4, 2026

Axsome Therapeutics closed at $137.00 on Nov 4, down 1.87%, within 1.5% of its 52-week closing low. Volume of 1.0M shares was 0.94× its 20-day average (close to normal).

Split-adjusted performance: -21.4% over one month, -38.5% over six months, +0.9% over one year.

In the quarter ended Sep 30, 2026, revenue was $259.69M, up 51.9% from a year earlier, with a net margin of -5.0%.

Short interest was 3.1M shares at the Oct 15 settlement, down 5.9% from the prior report (7.6% of float, 3.3 days to cover).

Market cap$7.18B52.4M shares
Revenue · quarter$259.7M+51.9% YoY
Diluted EPS$-0.25—
P/E · TTM—P/S 8.3×
Net margin-5.0%Gross 93.1%
Dividend yieldNone
52-week range134.93 – 255.17−46.3% from high
Volume1.0M0.94× 20-day avg
Volatility · 60d38.0%Annualised
Short % of float7.6%3.3 days to cover
Net cash$116.6MCash $313.9M
Next earnings—Not scheduled
Split-adjusted performance
1W −4.5%1M −21.4%3M −34.8%6M −38.5%YTD −25.0%1Y +0.9%3Y +128.2%5Y +249.1%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum35
Revenue growth79
Net margin66
Value (low P/E)—
Size92

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short3.1M−5.9% vs prior
Days to cover3.3Settled Oct 15
% of float7.6%
Short vol. 10d56.7%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
AXSMAxsome Therapeutics$137.00−1.87%−38.5%+51.9%−5.0%—$7.18B
AMRXAmneal Pharmaceuticals$19.95−1.29%+46.5%+9.9%7.2%44.2$6.95BCompare
KNSAKiniksa Pharmaceuticals International$96.12+3.03%+65.1%+58.1%16.6%68.9$7.55BCompare
RYTMRhythm Pharmaceuticals$110.68+28.04%+14.6%+46.9%−70.7%—$7.62BCompare
ORKAOruka Therapeutics$101.41+1.87%+45.3%———$6.71BCompare
ALKSAlkermes$45.89+0.44%+29.9%+21.8%3.4%—$7.70BCompare
IONSIonis Pharmaceuticals$40.15−0.67%−47.8%−40.7%−42.8%—$6.67BCompare
PRAXPraxis Precision Medicines$284.79+1.53%−15.8%———$7.95BCompare
LGNDLigand Pharmaceuticals$316.13+0.83%+35.9%−31.8%−36.2%122.9$6.32BCompare

Quick answers

What does Axsome Therapeutics do?
Axsome Therapeutics Inc is a clinical-stage biopharmaceutical company. It is engaged in developing novel therapies for the management of the central nervous system, or CNS, disorders for which there are limited treatment options.
What is AXSM's market cap?
$7.18B, based on the Nov 4 close of $137.00.
Does Axsome Therapeutics pay a dividend?
No regular cash dividend has been paid in the last year.
How much of AXSM is sold short?
3.1M shares, 7.6% of float, as of Oct 15, 2026.
What sector is AXSM in?
Healthcare, in the Pharmaceuticals industry.

About Axsome Therapeutics

Axsome Therapeutics Inc is a clinical-stage biopharmaceutical company. It is engaged in developing novel therapies for the management of the central nervous system, or CNS, disorders for which there are limited treatment options. Its pipeline products include AXS-05, AXS-07, AXS-12, and AXS-14. It manages its business as one operating segment and reporting unit, which is the business of developing and delivering novel therapies for the management of CNS disorders.

HQ: New York, NY925 employeesListed Nov 19, 2015axsome.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology