Upstream Bio financials
$5.27+1.54%
Close Sep 30, 2026 · split-adjustedRevenue
Net income
Income statement & cash flow
| Quarter | Q2 '26 Jun 30 | Q1 '26 Mar 31 | Q4 '25 Dec 31 | Q3 '25 Sep 30 | Q2 '25 Jun 30 | Q1 '25 Mar 31 | Q4 '24 Dec 31 |
|---|---|---|---|---|---|---|---|
| Revenue | $773.0K | $1.0M | $668.0K | $683.0K | $937.0K | $566.0K | $613.0K |
| Gross profit | $773.0K | $1.0M | $668.0K | $683.0K | $937.0K | $566.0K | $613.0K |
| Gross margin | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% |
| Operating income | -$42.4M | -$43.6M | -$46.2M | -$37.8M | -$44.3M | -$32.0M | -$26.3M |
| Net income | -$39.7M | -$40.6M | -$42.5M | -$33.7M | -$40.0M | -$27.3M | -$21.8M |
| Net margin | −5136.1% | −3925.6% | −6356.1% | −4941.1% | −4265.3% | −4818.0% | −3554.6% |
| Diluted EPS | $-0.73 | $-0.75 | $-0.78 | $-0.63 | $-0.74 | $-0.51 | $-0.48 |
| EBITDA | -$42.3M | -$43.6M | -$46.1M | -$37.8M | -$44.3M | -$32.0M | -$26.3M |
| Operating cash flow | -$35.6M | -$47.9M | -$30.6M | -$22.2M | -$39.2M | -$41.2M | -$19.6M |
| Free cash flow | -$35.6M | -$47.9M | -$30.7M | -$22.3M | -$39.3M | -$41.2M | -$19.8M |
| Diluted shares | 54.6M | 54.3M | 54.1M | 53.9M | 53.8M | 53.6M | 45.7M |
Balance sheet
| Period end | Jun 30 | Mar 31 | Dec 31 | Sep 30 | Jun 30 | Mar 31 |
|---|---|---|---|---|---|---|
| Cash & equivalents | $79.4M | $96.7M | $101.6M | $72.2M | $45.5M | $71.3M |
| Short-term investments | $181.9M | $197.9M | $239.9M | $300.3M | $348.1M | $360.1M |
| Total debt | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 |
| Total assets | $281.2M | $318.1M | $353.8M | $391.2M | $420.5M | $456.2M |
| Total liabilities | $10.2M | $14.1M | $14.0M | $12.6M | $11.8M | $10.6M |
| Shareholders' equity | $271.0M | $304.0M | $339.8M | $378.6M | $408.7M | $445.6M |
From SEC filings via Massive. Fiscal periods follow the company's own calendar; free cash flow is operating cash flow minus capital expenditure.
Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology