NASDAQ · TYRAHealthcarePharmaceuticals

Tyra Biosciences, Inc. Common Stock (TYRA)

$21.53+0.73%
Close Nov 4, 2026 · split-adjusted
Nov 4, 2026$21.52▲ 43.50% in range
Nov 4, 2025Low $14.28 · High $39.61Nov 4, 2026
What changed · written from our data
As of Nov 4, 2026

Tyra Biosciences closed at $21.52 on Nov 4, up 0.73%, 45.7% below its 52-week closing high. Volume of 542.9K shares was 0.92× its 20-day average (close to normal).

Split-adjusted performance: +6.3% over one month, -36.3% over six months, +39.5% over one year.

Short interest was 9.5M shares at the Oct 15 settlement (26.5% of float, 15.3 days to cover).

Market cap$1.48B68.8M shares
Revenue · quarter$0.00—
Diluted EPS$-0.69—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range14.28 – 39.61−45.7% from high
Volume542.9K0.92× 20-day avg
Volatility · 60d74.2%Annualised
Short % of float26.5%15.3 days to cover
Net cash$353.9MCash $353.9M
Next earnings—Not scheduled
Split-adjusted performance
1W −1.0%1M +6.3%3M −20.2%6M −36.3%YTD −18.1%1Y +39.5%3Y +88.3%5Y −4.2%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum37
Revenue growth—
Net margin—
Value (low P/E)—
Size76

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short9.5M+0.9% vs prior
Days to cover15.3Settled Oct 15
% of float26.5%
Short vol. 10d66.6%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
TYRATyra Biosciences$21.53+0.73%−36.3%———$1.48B
RAPPRapport Therapeutics$25.93+1.93%−30.0%———$1.46BCompare
MLYSMineralys Therapeutics$17.00+6.32%−43.6%———$1.50BCompare
KARDKardigan$15.56+8.66%————$1.45BCompare
PCRXPacira BioSciences$36.40+0.03%+53.7%+6.2%2.4%99.2$1.45BCompare
ETONEton Pharmaceutcials$50.72−0.45%+68.2%+98.6%30.8%114.3$1.45BCompare
INVAInnoviva$21.26+1.58%−5.6%+19.3%−69.8%4.3$1.54BCompare
ANABAnaptysBio$47.51−0.46%−29.5%−8.0%−206.9%—$1.42BCompare
DMRADamora Therapeutics$22.94+3.89%————$1.42BCompare

Quick answers

What does Tyra Biosciences do?
Tyra Biosciences Inc is a clinical-stage biotechnology company focused on developing next-generation precision medicines for large opportunities in targeted oncology and genetically defined conditions, harnessing the power of Fibroblast Growth Factor Receptor (FGFR) biology. The company's in-house precision medicine platform, SNAP, enables rapid and precise drug design through iterative molecular SNAPshots that help to design and predict which product candidates may demonstrate the highest potency, selectivity, and tolerability in the clinic.
What is TYRA's market cap?
$1.48B, based on the Nov 4 close of $21.52.
Does Tyra Biosciences pay a dividend?
No regular cash dividend has been paid in the last year.
How much of TYRA is sold short?
9.5M shares, 26.5% of float, as of Oct 15, 2026.
What sector is TYRA in?
Healthcare, in the Pharmaceuticals industry.

About Tyra Biosciences

Tyra Biosciences Inc is a clinical-stage biotechnology company focused on developing next-generation precision medicines for large opportunities in targeted oncology and genetically defined conditions, harnessing the power of Fibroblast Growth Factor Receptor (FGFR) biology. The company's in-house precision medicine platform, SNAP, enables rapid and precise drug design through iterative molecular SNAPshots that help to design and predict which product candidates may demonstrate the highest potency, selectivity, and tolerability in the clinic. The various drug candidates in the company's product pipeline are FGFR3, FGFR4/3, and FGFR1/2/3: three clinical-stage, novel small molecules designed to overcome the toxicity and resistance liabilities of first-generation pan-FGFR inhibitors.

HQ: Carlsbad, CA87 employeesListed Sep 15, 2021tyra.bio

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology