NASDAQ · SNDXHealthcarePharmaceuticals

Syndax Pharmaceuticals, Inc. (SNDX)

$10.45−26.87%
Close Nov 4, 2026 · split-adjusted
Nov 4, 2026$10.45▼ 31.92% in range
Nov 4, 2025Low $10.45 · High $25.15Nov 4, 2026
What changed · written from our data
As of Nov 4, 2026

Syndax Pharmaceuticals closed at $10.45 on Nov 4, down 26.87%, within 0.0% of its 52-week closing low. Volume of 15.1M shares was 4.95× its 20-day average (well above normal).

Split-adjusted performance: -39.8% over one month, -49.4% over six months, -24.1% over one year.

In the quarter ended Sep 30, 2026, revenue was $83.30M, up 81.6% from a year earlier, with a net margin of -59.3%.

Short interest was 18.0M shares at the Oct 15 settlement, down 1.3% from the prior report (21.4% of float, 7.6 days to cover).

Market cap$933.2M89.3M shares
Revenue · quarter$83.3M+81.6% YoY
Diluted EPS$-0.55—
P/E · TTM—P/S 3.2×
Net margin-59.3%Gross 83.2%
Dividend yieldNone
52-week range10.45 – 25.15−58.4% from high
Volume15.1M4.95× 20-day avg
Volatility · 60d84.0%Annualised
Short % of float21.4%7.6 days to cover
Net cash$182.3MCash $427.1M
Next earnings—Not scheduled
Split-adjusted performance
1W −27.0%1M −39.8%3M −47.1%6M −49.4%YTD −50.3%1Y −24.1%3Y −19.9%5Y −43.8%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum25
Revenue growth84
Net margin45
Value (low P/E)—
Size70

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short18.0M−1.3% vs prior
Days to cover7.6Settled Oct 15
% of float21.4%
Short vol. 10d45.7%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
SNDXSyndax Pharmaceuticals$10.45−26.87%−49.4%+81.6%−59.3%—$933.2M
LTGOLatigo Biotherapeutics$14.04−3.64%————$930.8MCompare
ANROAlto Neuroscience$23.30+2.64%−4.9%———$914.3MCompare
JBIOJade Biosciences$15.04+3.23%−40.2%———$956.5MCompare
SVRASavara$4.66−1.89%−11.6%———$957.4MCompare
RIGLRigel Pharmaceuticals Inc. (New)$51.29+4.97%+92.3%−22.6%22.0%3.0$958.1MCompare
ORICOric Pharmaceuticals$9.34−2.61%+0.4%———$968.1MCompare
CRVSCorvus Pharmaceuticals$10.57+7.53%−31.6%———$889.2MCompare
MLTXMoonLake Immunotherapeutics$11.56−1.20%−34.7%———$983.8MCompare

Quick answers

What does Syndax Pharmaceuticals do?
Syndax Pharmaceuticals Inc is a clinical-stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. Its product candidates include revumenib and axatilimab.
What is SNDX's market cap?
$933.15M, based on the Nov 4 close of $10.45.
Does Syndax Pharmaceuticals pay a dividend?
No regular cash dividend has been paid in the last year.
How much of SNDX is sold short?
18.0M shares, 21.4% of float, as of Oct 15, 2026.
What sector is SNDX in?
Healthcare, in the Pharmaceuticals industry.

About Syndax Pharmaceuticals

Syndax Pharmaceuticals Inc is a clinical-stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. Its product candidates include revumenib and axatilimab. It is developing revumenib, a selective menin-MLL inhibitor for KMT2A-rearranged (MLL-r) and NPM1-mutant acute leukemias, including ALL and AML. It is also developing axatilimab, a CSF-1R-blocking antibody for cGVHD and idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells. The business activity of the group is functioned through the region of the United States.

HQ: New York, NY298 employeesListed Mar 3, 2016syndax.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology