NASDAQ · OMERHealthcarePharmaceuticals

Omeros Corporation (OMER)

$17.17−5.56%
Close Nov 5, 2026 · split-adjusted
Nov 4, 2026$18.18▲ 170.13% in range
Nov 4, 2025Low $6.28 · High $21.05Nov 4, 2026
What changed · written from our data
As of Nov 5, 2026

Omeros closed at $17.17 on Nov 5, down 5.56%, 18.4% below its 52-week closing high. Volume of 537.6K shares was 0.46× its 20-day average (below normal).

Split-adjusted performance: -8.4% over one month, +17.3% over six months, +155.1% over one year.

In the quarter ended Jun 30, 2026, revenue was $28.53M, with a net margin of 46.4%.

Short interest was 11.4M shares at the Oct 15 settlement (17.8% of float, 12.2 days to cover).

Market cap$1.24B72.4M shares
Revenue · quarter$28.5M—
Diluted EPS$0.15—
P/E · TTM10.0×P/S 32.3×
Net margin46.4%Gross 97.2%
Dividend yieldNone
52-week range6.28 – 21.05−18.4% from high
Volume537.6K0.46× 20-day avg
Volatility · 60d77.7%Annualised
Short % of float17.8%12.2 days to cover
Net cash$58.7MCash $132.0M
Next earnings—Not scheduled
Split-adjusted performance
1W −9.4%1M −8.4%3M +29.6%6M +17.3%YTD 0.0%1Y +155.1%3Y +1342.9%5Y +167.4%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 418 companies (100 = best)

6-month momentum83
Revenue growth—
Net margin95
Value (low P/E)68
Size73

Industry medians: 6-month return −27.4%, revenue growth +5.9%, net margin −37.5%, P/E 15.1×.

Short interest

Details →
Shares short11.4M+0.4% vs prior
Days to cover12.2Settled Oct 15
% of float17.8%
Short vol. 10d65.4%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
OMEROmeros$17.17−5.56%+17.3%—46.4%10.0$1.24B
LBRXLB Pharmaceuticals$38.74−5.18%+21.1%———$1.25BCompare
NKTRNektar Therapeutics$36.01−6.42%−56.8%−9.3%−401.0%—$1.23BCompare
OPKOpko Health$1.69−4.47%+51.0%+4.3%−5.1%—$1.26BCompare
MNKDMannkind$3.75−4.61%+5.6%+42.9%−17.4%—$1.21BCompare
URGNUroGen Pharma$26.21−8.80%−1.4%+199.2%−19.8%—$1.29BCompare
AMPHAmphastar Pharmaceuticals$27.86−0.59%+15.9%+5.4%16.5%15.1$1.18BCompare
AVLNAvalyn Pharma$26.55−3.35%————$1.18BCompare
DMRADamora Therapeutics$21.32−7.08%————$1.32BCompare

Quick answers

What does Omeros do?
Omeros Corp is an inventive, commercial-stage biotechnology company that discovers and develops first-in-class protein and small-molecule therapeutics for large-market and orphan indications, with particular emphasis on complement-mediated diseases, cancers, and addictive or compulsive disorders. The company's clinical-stage development programs include: narsoplimab, its antibody targeting mannan-binding lectin-associated serine protease 2 (MASP-2), the effector enzyme of the lectin pathway of complement; OMS1029, its long-acting antibody targeting MASP-2; and OMS527, its phosphodiesterase 7 (PDE7) inhibitor program.
What is OMER's market cap?
$1.24B, based on the Nov 5 close of $17.17.
What is OMER's P/E ratio?
10.0× trailing-twelve-month earnings of $124.83M.
Does Omeros pay a dividend?
No regular cash dividend has been paid in the last year.
How much of OMER is sold short?
11.4M shares, 17.8% of float, as of Oct 15, 2026.
What sector is OMER in?
Healthcare, in the Pharmaceuticals industry.

About Omeros

Omeros Corp is an inventive, commercial-stage biotechnology company that discovers and develops first-in-class protein and small-molecule therapeutics for large-market and orphan indications, with particular emphasis on complement-mediated diseases, cancers, and addictive or compulsive disorders. The company's clinical-stage development programs include: narsoplimab, its antibody targeting mannan-binding lectin-associated serine protease 2 (MASP-2), the effector enzyme of the lectin pathway of complement; OMS1029, its long-acting antibody targeting MASP-2; and OMS527, its phosphodiesterase 7 (PDE7) inhibitor program.

HQ: Seattle, WA175 employeesListed Oct 8, 2009omeros.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology