NASDAQ · NBIXHealthcareBiotechnology

Neurocrine Biosciences Inc (NBIX)

$166.05+0.73%
Close Nov 4, 2026 · split-adjusted
Nov 4, 2026$166.05▲ 15.96% in range
Nov 4, 2025Low $123.10 · High $185.50Nov 4, 2026
What changed · written from our data
As of Nov 4, 2026

Neurocrine Biosciences closed at $166.05 on Nov 4, up 0.73%, 10.5% below its 52-week closing high. Volume of 2.3M shares was 1.66× its 20-day average (above normal).

Split-adjusted performance: +14.1% over one month, +12.9% over six months, +17.0% over one year.

In the quarter ended Sep 30, 2026, revenue was $1.12B, up 41.2% from a year earlier, with a net margin of 18.4%.

Short interest was 6.4M shares at the Oct 15 settlement, up 10.2% from the prior report (6.6% of float, 4.5 days to cover).

Market cap$16.88B101.6M shares
Revenue · quarter$1.12B+41.2% YoY
Diluted EPS$1.96−3.9% YoY
P/E · TTM24.0×P/S 4.6×
Net margin18.4%Gross 97.6%
Dividend yieldNone
52-week range123.10 – 185.50−10.5% from high
Volume2.3M1.66× 20-day avg
Volatility · 60d36.5%Annualised
Short % of float6.6%4.5 days to cover
Net cash$737.9MCash $737.9M
Next earnings—Not scheduled
Split-adjusted performance
1W +14.1%1M +14.1%3M +3.9%6M +12.9%YTD +17.1%1Y +17.0%3Y +55.0%5Y +64.0%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Biotechnology

Percentile among 139 companies (100 = best)

6-month momentum73
Revenue growth77
Net margin80
Value (low P/E)46
Size96

Industry medians: 6-month return −19.2%, revenue growth +8.8%, net margin −312.9%, P/E 22.0×.

Short interest

Details →
Shares short6.4M+10.2% vs prior
Days to cover4.5Settled Oct 15
% of float6.6%
Short vol. 10d64.8%of daily volume

Closest peers by size in Biotechnology

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
NBIXNeurocrine Biosciences$166.05+0.73%+12.9%+41.2%18.4%24.0$16.88B
EXELExelixis$72.75+0.61%+49.4%+10.2%33.1%20.1$17.75BCompare
HALOHalozyme Therapeutics$130.34+1.34%+96.4%+47.7%47.8%35.8$14.79BCompare
KYMRKymera Therapeutics$136.25+7.21%+58.0%−100.0%——$11.63BCompare
TECHBio-Techne$72.73+0.10%+53.4%+1.3%17.0%62.8$11.42BCompare
RGENRepligen$178.20−0.04%+41.7%+10.9%−18.4%—$11.31BCompare
PCVXVaxcyte$65.68+8.01%+15.0%———$10.34BCompare
IBRXImmunityBio$8.93+7.72%+6.6%+93.9%−449.6%—$9.46BCompare
TWSTTwist Bioscience$142.58+1.63%+139.5%+23.2%−29.6%—$9.45BCompare

Quick answers

What does Neurocrine Biosciences do?
Neurocrine Biosciences Inc is a biopharmaceutical firm focused on the research, development, and commercialization of treatments for neurological, psychiatric, endocrine, and immunological disorders. Its portfolio includes therapies for conditions such as tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, and treatments for endometriosis and uterine fibroids.
What is NBIX's market cap?
$16.88B, based on the Nov 4 close of $166.05.
What is NBIX's P/E ratio?
24.0× trailing-twelve-month earnings of $702.50M.
Does Neurocrine Biosciences pay a dividend?
No regular cash dividend has been paid in the last year.
How much of NBIX is sold short?
6.4M shares, 6.6% of float, as of Oct 15, 2026.
What sector is NBIX in?
Healthcare, in the Biotechnology industry.

About Neurocrine Biosciences

Neurocrine Biosciences Inc is a biopharmaceutical firm focused on the research, development, and commercialization of treatments for neurological, psychiatric, endocrine, and immunological disorders. Its portfolio includes therapies for conditions such as tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, and treatments for endometriosis and uterine fibroids. The company also maintains a pipeline of drug candidates in various stages of clinical and preclinical development across its therapeutic areas, including small molecules, peptides, proteins, antibodies, conjugates, and gene therapies. It derives revenue from the sale of its pharmaceutical products.

HQ: San Diego, CA2,500 employeesListed May 23, 1996neurocrine.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology