NASDAQ · LONAHealthcareBiotechnology

LeonaBio, Inc. Common Stock (LONA)

$4.34−4.93%
Close Nov 5, 2026 · split-adjusted
Nov 5, 2026$4.34▼ 33.74% in range
Jan 12, 2026Low $2.87 · High $11.68Nov 5, 2026
What changed · written from our data
As of Nov 5, 2026

LeonaBio closed at $4.34 on Nov 5, down 4.93%, 62.8% below its highest close since Jan 12. Volume of 94.7K shares was 1.14× its 20-day average (close to normal).

Split-adjusted performance: -25.6% over one month, -56.0% over six months.

Short interest was 87.3K shares at the Oct 15 settlement, up 355.7% from the prior report (1.8% of float, 1.0 days to cover).

Market cap$40.9M9.4M shares
Revenue · quarter$0.00—
Diluted EPS$-0.80—
P/E · TTM—
Net margin—
Dividend yieldNone
Range since Jan 122.87 – 11.68−62.8% from high
Volume94.7K1.14× 20-day avg
Volatility · 60d138.9%Annualised
Short % of float1.8%1.0 days to cover
Net cash$51.1MCash $51.1M
Next earnings—Not scheduled
Split-adjusted performance
1W −11.6%1M −25.6%3M −43.5%6M −56.0%YTD —1Y —3Y —5Y —

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Biotechnology

Percentile among 139 companies (100 = best)

6-month momentum24
Revenue growth—
Net margin—
Value (low P/E)—
Size23

Industry medians: 6-month return −24.8%, revenue growth +8.5%, net margin −226.4%, P/E 21.0×.

Short interest

Details →
Shares short87.3K+355.7% vs prior
Days to cover1.0Settled Oct 15
% of float1.8%
Short vol. 10d52.6%of daily volume

Closest peers by size in Biotechnology

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
LONALeonaBio$4.34−4.93%−56.0%———$40.9M
EXOZeXoZymes$4.11−4.64%−58.9%———$38.2MCompare
CRBUCaribou Biosciences$0.4123−7.22%−78.1%−43.8%−1619.9%—$44.2MCompare
PTHSPelthos Therapeutics$9.30−8.37%−62.8%—−150.1%—$36.6MCompare
INMBINmune Bio$1.18−11.65%−17.8%———$36.4MCompare
IMAImageneBio$4.17+1.59%−29.5%———$47.3MCompare
TILInstil Bio$6.990.00%−13.0%———$47.4MCompare
GRMLGreenland Mines$3.57−8.70%————$48.9MCompare
ELUTElutia$0.7509−1.15%−24.8%−11.6%−315.0%0.6$33.3MCompare

Quick answers

What does LeonaBio do?
LeonaBio Inc is a clinical-stage biopharmaceutical company focused on the development of novel therapeutics for high unmet medical needs. Its key drug candidates, lasofoxifene and ATH-1105, are novel, small-molecule therapies with the potential to address treatment-resistant metastatic breast cancer and amyotrophic lateral sclerosis (ALS).
What is LONA's market cap?
$40.89M, based on the Nov 5 close of $4.34.
Does LeonaBio pay a dividend?
No regular cash dividend has been paid in the last year.
How much of LONA is sold short?
87.3K shares, 1.8% of float, as of Oct 15, 2026.
What sector is LONA in?
Healthcare, in the Biotechnology industry.

About LeonaBio

LeonaBio Inc is a clinical-stage biopharmaceutical company focused on the development of novel therapeutics for high unmet medical needs. Its key drug candidates, lasofoxifene and ATH-1105, are novel, small-molecule therapies with the potential to address treatment-resistant metastatic breast cancer and amyotrophic lateral sclerosis (ALS). LeonaBio is also exploring the use of other drug candidates that enhance the neurotrophic HGF system, including ATH-1020, to improve neuronal health and function in multiple neurological diseases. In addition, it is also focused on designing and testing new early compounds directed towards novel targets for a variety of clinical applications. The company operates as a single operating segment, developing and commercializing therapeutics.

HQ: Bothell, WA19 employeesListed Sep 18, 2020leonabio.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology