NASDAQ · GPCRHealthcarePharmaceuticals

Structure Therapeutics Inc. American Depositary Shares (GPCR)

$19.84−5.30%
Close Nov 12, 2026 · split-adjusted
Nov 9, 2026$21.78▼ 35.75% in range
Nov 10, 2025Low $19.08 · High $93.79Nov 9, 2026
What changed · written from our data
As of Nov 12, 2026

Structure Therapeutics Inc. American Depositary Shares closed at $19.84 on Nov 12, down 5.30%, 78.8% below its 52-week closing high. Volume of 1.0M shares was 1.03× its 20-day average (close to normal).

Split-adjusted performance: -9.3% over one month, -50.2% over six months, -43.1% over one year.

Short interest was 5.9M shares at the Oct 30 settlement, down 17.1% from the prior report (6.5 days to cover).

Market cap$1.41B71.3M shares
Revenue · quarter$0.00—
Diluted EPS$-0.66—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range19.08 – 93.79−78.8% from high
Volume1.0M1.03× 20-day avg
Volatility · 60d61.5%Annualised
Short % of float—6.5 days to cover
Net cash$1.24BCash $1.24B
Next earnings—Not scheduled
Split-adjusted performance
1W +4.0%1M −9.3%3M −63.6%6M −50.2%YTD −71.5%1Y −43.1%3Y −71.9%5Y —

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 417 companies (100 = best)

6-month momentum—
Revenue growth—
Net margin—
Value (low P/E)—
Size—

Industry medians: 6-month return −26.3%, revenue growth +9.3%, net margin −35.1%, P/E 16.5×.

Short interest

Details →
Shares short5.9M−17.1% vs prior
Days to cover6.5Settled Oct 30
% of float—
Short vol. 10d44.1%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
GPCRStructure Therapeutics$19.84−5.30%−50.2%———$1.41B
CMPSCOMPASS Pathways Plc American Depository Shares$9.12−1.94%−14.1%———$1.29BCompare
SLNSilence Therapeutics Plc American Depository Share$19.80+0.15%+177.7%———$1.23BCompare
ZLABZai Lab Limited$26.04−1.44%+28.1%−6.8%−42.6%—$3.22BCompare
AMRNAmarin$11.67−0.34%−21.0%−20.4%0.6%—$490.6MCompare
BCYCBicycle Therapeutics$3.45−6.50%−26.1%+190.2%−30.8%—$241.8MCompare
KZIAKazia Therapeutics Limited$6.95−6.46%−49.7%———$108.1MCompare
MREOMereo BioPharma Group$0.3050−0.52%+24.0%———$48.7MCompare
ONCBeOne Medicines$415.96−0.96%+36.6%+33.8%20.4%51.9$47.51BCompare

Quick answers

What does Structure Therapeutics Inc. American Depositary Shares do?
Structure Therapeutics Inc is a clinical-stage biopharmaceutical company developing novel oral small-molecule therapeutics to treat a wide range of chronic diseases with unmet medical needs. Its differentiated technology platform leverages both structure-based drug discovery and expertise in computational chemistry to discover and develop small molecule therapeutics against G-protein coupled receptors (GPCRs).
What is GPCR's market cap?
$1.41B, based on the Nov 12 close of $19.84.
What sector is GPCR in?
Healthcare, in the Pharmaceuticals industry.

About Structure Therapeutics

Structure Therapeutics Inc is a clinical-stage biopharmaceutical company developing novel oral small-molecule therapeutics to treat a wide range of chronic diseases with unmet medical needs. Its differentiated technology platform leverages both structure-based drug discovery and expertise in computational chemistry to discover and develop small molecule therapeutics against G-protein coupled receptors (GPCRs). The group operates and manages its business as one reportable and operating segment, which is the business of research and development of medicines that target chronic diseases with unmet medical needs.

HQ: South San Francisco, CA281 employeesListed Feb 3, 2023structuretx.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology