NASDAQ · FULCHealthcarePharmaceuticals

Fulcrum Therapeutics, Inc. Common Stock (FULC)

$3.77+0.80%
Close Nov 4, 2026 · split-adjusted
Nov 3, 2026$3.76▼ 58.31% in range
Nov 3, 2025Low $3.14 · High $14.60Nov 3, 2026
What changed · written from our data
As of Nov 4, 2026

Fulcrum Therapeutics closed at $3.77 on Nov 4, up 0.80%, 74.2% below its 52-week closing high. Volume of 777.2K shares was 0.54× its 20-day average (below normal).

Split-adjusted performance: +2.2% over one month, -47.0% over six months, -58.2% over one year.

Short interest was 6.8M shares at the Oct 15 settlement, down 5.0% from the prior report (10.6% of float, 4.7 days to cover).

Market cap$288.0M76.4M shares
Revenue · quarter$0.00—
Diluted EPS$-0.34—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range3.14 – 14.60−74.2% from high
Volume777.2K0.54× 20-day avg
Volatility · 60d15.0%Annualised
Short % of float10.6%4.7 days to cover
Net cash$318.8MCash $318.8M
Next earnings—Not scheduled
Split-adjusted performance
1W +0.5%1M +2.2%3M 0.0%6M −47.0%YTD −66.7%1Y −58.2%3Y +12.5%5Y −83.8%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum28
Revenue growth—
Net margin—
Value (low P/E)—
Size53

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short6.8M−5.0% vs prior
Days to cover4.7Settled Oct 15
% of float10.6%
Short vol. 10d43.8%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
FULCFulcrum Therapeutics$3.77+0.80%−47.0%———$288.0M
LRMRLarimar Therapeutics$2.76+8.66%−33.5%———$286.7MCompare
RCKTRocket Pharmaceuticals$2.61+3.98%−32.4%———$286.5MCompare
VOGXVogenx$19.73−3.90%————$293.1MCompare
TTRXTurn Therapeutics$9.80+3.05%+158.2%———$297.6MCompare
EBSEmergent Biosolutions$5.90−5.60%−35.2%−52.4%−29.7%—$302.5MCompare
SPRYARS Pharmaceuticals$3.050.00%−67.1%+114.2%−185.2%—$303.3MCompare
BIOABioAge Labs$5.95−0.17%−67.8%+1.6%−1064.7%—$273.1MCompare
ARCTArcturus Therapeutics Holdings$10.87+13.94%+19.1%−89.5%−803.8%—$309.0MCompare

Quick answers

What does Fulcrum Therapeutics do?
Fulcrum Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing small molecules for genetically defined rare diseases. Its product candidate, Pociredir, is an oral small molecule designed to induce fetal hemoglobin (HbF) and is in clinical development for sickle cell disease (SCD).
What is FULC's market cap?
$287.96M, based on the Nov 4 close of $3.77.
Does Fulcrum Therapeutics pay a dividend?
No regular cash dividend has been paid in the last year.
How much of FULC is sold short?
6.8M shares, 10.6% of float, as of Oct 15, 2026.
What sector is FULC in?
Healthcare, in the Pharmaceuticals industry.

About Fulcrum Therapeutics

Fulcrum Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing small molecules for genetically defined rare diseases. Its product candidate, Pociredir, is an oral small molecule designed to induce fetal hemoglobin (HbF) and is in clinical development for sickle cell disease (SCD). The company completed dosing in the Phase 1b PIONEER trial evaluating pociredir in adults with SCD and reported clinical data showing clinically relevant HbF induction and improvements in markers of hemolysis and anemia. The company has also generated a pipeline of clinical-stage and pre-clinical programs targeting the root causes of rare genetic diseases.

HQ: Cambridge, MA55 employeesListed Jul 18, 2019fulcrumtx.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology