NASDAQ · APVOHealthcarePharmaceuticals

Aptevo Therapeutics Inc (APVO)

$1.37+0.74%
Close Nov 4, 2026 · split-adjusted
Nov 3, 2026$1.36▼ 94.86% in range
Nov 3, 2025Low $1.28 · High $28.08Nov 3, 2026
What changed · written from our data
As of Nov 4, 2026

Aptevo Therapeutics closed at $1.37 on Nov 4, up 0.74%, 95.1% below its 52-week closing high. Volume of 14.8K shares was 0.33× its 20-day average (below normal).

Split-adjusted performance: -23.7% over one month, -72.3% over six months, -94.8% over one year.

Short interest was 96.5K shares at the Oct 15 settlement, down 19.2% from the prior report (5.8% of float, 1.9 days to cover).

Market cap$2.5M1.8M shares
Revenue · quarter$0.00—
Diluted EPS$-5.31—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range1.28 – 28.08−95.1% from high
Volume14.8K0.33× 20-day avg
Volatility · 60d112.4%Annualised
Short % of float5.8%1.9 days to cover
Net cash$9.8MCash $9.8M
Next earnings—Not scheduled
Split-adjusted performance
1W +5.4%1M −23.7%3M −66.3%6M −72.3%YTD −85.5%1Y −94.8%3Y −100.0%5Y −100.0%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum11
Revenue growth—
Net margin—
Value (low P/E)—
Size5

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short96.5K−19.2% vs prior
Days to cover1.9Settled Oct 15
% of float5.8%
Short vol. 10d24.5%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
APVOAptevo Therapeutics$1.37+0.74%−72.3%———$2.5M
HCWBHCW Biologics$1.08−6.09%−48.6%+1969.7%−11340.3%—$2.4MCompare
REVBRevelation Biosciences$4.12−7.05%−42.3%———$2.3MCompare
ERNAErnexa Therapeutics$1.99−1.49%−67.1%———$2.3MCompare
SILOSilo Pharma$1.33+3.91%−78.9%−100.0%——$2.9MCompare
GRIGRI Bio$1.43−7.14%−39.4%———$3.1MCompare
SBFMSunshine Biopharma$2.65−3.28%−98.8%−1.6%−16.9%—$2.0MCompare
MBIOMustang Bio$0.4138+1.07%−44.6%———$3.1MCompare
JUNSJupiter Neurosciences$2.46+1.23%−91.0%—−9380.9%—$3.2MCompare

News about Aptevo Therapeutics

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Quick answers

What does Aptevo Therapeutics do?
Aptevo Therapeutics Inc is a clinical-stage research and development biotechnology company focused on developing novel immunotherapeutic candidates for the treatment of different forms of cancer. Its clinical candidates are; ALG.APV-527, which targets co-stimulatory receptors and tumor antigens, and CD3xCD123, which is being developed as a potential treatment of frontline acute myelogenous leukemia.
What is APVO's market cap?
$2.48M, based on the Nov 4 close of $1.37.
Does Aptevo Therapeutics pay a dividend?
No regular cash dividend has been paid in the last year.
How much of APVO is sold short?
96.5K shares, 5.8% of float, as of Oct 15, 2026.
What sector is APVO in?
Healthcare, in the Pharmaceuticals industry.

About Aptevo Therapeutics

Aptevo Therapeutics Inc is a clinical-stage research and development biotechnology company focused on developing novel immunotherapeutic candidates for the treatment of different forms of cancer. Its clinical candidates are; ALG.APV-527, which targets co-stimulatory receptors and tumor antigens, and CD3xCD123, which is being developed as a potential treatment of frontline acute myelogenous leukemia. The company's preclinical candidates, APVO711, CD3xCD123, APVO0442, and APVO603, are being developed using the ADAPTIR modular protein technology platform. The company's versatile and robust ADAPTIR and ADAPTIR-FLEX platforms are designed to generate monospecific, bispecific, and multi-specific antibody candidates that are capable of enhancing the human immune system against cancer cells.

HQ: Seattle, WA33 employeesListed Jul 20, 2016aptevotherapeutics.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology