NASDAQ · ANNXHealthcarePharmaceuticals

Annexon, Inc. Common Stock (ANNX)

$4.33+3.34%
Close Nov 4, 2026 · split-adjusted
Nov 3, 2026$4.19▲ 32.18% in range
Nov 3, 2025Low $2.68 · High $6.96Nov 3, 2026
What changed · written from our data
As of Nov 4, 2026

Annexon closed at $4.33 on Nov 4, up 3.34%, 37.8% below its 52-week closing high. Volume of 4.5M shares was 1.25× its 20-day average (close to normal).

Split-adjusted performance: +7.4% over one month, -24.0% over six months, +36.6% over one year.

Short interest was 31.6M shares at the Oct 15 settlement, down 1.2% from the prior report (20.6% of float, 10.3 days to cover).

Market cap$820.9M189.6M shares
Revenue · quarter$0.00—
Diluted EPS$-0.28—
P/E · TTM—
Net margin—
Dividend yieldNone
52-week range2.68 – 6.96−37.8% from high
Volume4.5M1.25× 20-day avg
Volatility · 60d64.2%Annualised
Short % of float20.6%10.3 days to cover
Net cash$209.2MCash $209.2M
Next earnings—Not scheduled
Split-adjusted performance
1W +7.2%1M +7.4%3M −22.7%6M −24.0%YTD −13.7%1Y +36.6%3Y +89.9%5Y −74.6%

Earnings reactions

History →

No reported quarters with price history yet.

Rank within Pharmaceuticals

Percentile among 420 companies (100 = best)

6-month momentum52
Revenue growth—
Net margin—
Value (low P/E)—
Size68

Industry medians: 6-month return −25.5%, revenue growth +6.2%, net margin −33.8%, P/E 16.1×.

Short interest

Details →
Shares short31.6M−1.2% vs prior
Days to cover10.3Settled Oct 15
% of float20.6%
Short vol. 10d39.8%of daily volume

Closest peers by size in Pharmaceuticals

CompanyPriceToday6MRev. growthNet marginP/EMkt cap
ANNXAnnexon$4.33+3.34%−24.0%———$820.9M
ABUSArbutus Biopharma$4.06+4.64%−8.1%−90.6%−512.0%5.3$804.3MCompare
AKTSAktis Oncology$15.20+1.74%−24.1%—−713.5%—$845.4MCompare
CYRXCryoPort$16.70+1.52%+31.6%+7.7%−20.9%—$845.8MCompare
ALMSAlumis$6.55+0.77%−74.3%−37.7%−8557.2%—$847.8MCompare
ARDXArdelyx$3.29+8.58%−53.7%+15.7%−0.6%—$849.4MCompare
COLLCollegium Pharmaceutical$23.67−0.25%−35.2%+6.3%−7.5%16.1$770.6MCompare
CRVSCorvus Pharmaceuticals$10.57+7.53%−31.6%———$889.2MCompare
ANROAlto Neuroscience$23.30+2.64%−4.9%———$914.3MCompare

Quick answers

What does Annexon do?
Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q.
What is ANNX's market cap?
$820.88M, based on the Nov 4 close of $4.33.
Does Annexon pay a dividend?
No regular cash dividend has been paid in the last year.
How much of ANNX is sold short?
31.6M shares, 20.6% of float, as of Oct 15, 2026.
What sector is ANNX in?
Healthcare, in the Pharmaceuticals industry.

About Annexon

Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Its product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; ANX1502, for Oral small molecule; and ANX009, for systemic autoimmune diseases.

HQ: Brisbane, CA92 employeesListed Jul 24, 2020annexonbio.com

Sources: Massive / Polygon daily aggregates (split-adjusted) · SEC filings via Massive · FINRA settlements via Massive · Financial Modeling Prep. Figures are dated where shown; research is informational, not investment advice. Methodology